Mesothelioma and Work Exposure Mesothelioma is more common among those who work with asbestos. Firefighters, construction workers and veterans of the military are at higher risk. The lung's lining (pleural mesothelioma), or the abdomen, is the most common mesothelioma site. In rare cases, it may affect the heart or testicles. https://vimeo.com/704972081