The effectiveness of the antidote declines sharply after this time. If required the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. Management of patients World health organization https://brooksffbwr.isblog.net/sgt-78-in-uk-grundlagen-erkl-rt-36699017